We also found that PD-L1 was not expressed in conventional chondrosarcoma, while PD-L1 was detectable in DDCS, which was consistent with a previous study [26]; this PD-L1 expression difference is possibly because the dedifferentiated component in DDCS may be osteosarcoma, which can express PD-L1. This evidence concerns the gene CD274 and chondrosarcoma.