BRCA1 and ovarian carcinoma: Among the 40 (80.0%) young patients with positive first or second-degree family history of breast and/or ovarian cancer, 13 (32.5%) had deleterious/suspected deleterious BRCA1 or BRCA2 mutations, while no known mutations were found in the 10 other patients without a significant family history, p-value = 0.046.