ADA and Alzheimer disease: The normalized level of HO-1 mRNA in the ADA group [0.11 (0.04–0.24)] was significantly lower than the level in both the CG [0.30 (0.21–0.71), p = 0.049] and AD [0.84 (0.35–2.51), p = 0.021] groups (Figure 1).