SHH and cystic fibrosis: We used instead a treatment with the FgfR signaling inhibitor SU5402 (5 μM; between 8 hpf and 12 hpf), which results in a decrease of Shh expression in CF, therefore also indirectly mimicking the SF phenotype (Hinaux et al., 2016; Pottin et al., 2011), but with less deleterious effects on larval development.