A2M and polycystic ovary syndrome: Factors such as polycystic ovarian syndrome (PCOS), high FSH dosage, high ratio between luteinizing hormone (LH)/ FSH, high human chorionic gonadotrophin (hCG) dosage, high inhibin A and B levels, high vascular endothelial growth factor, and other interleukins levels, and decreased alpha-2-macroglobulin levels are considered as OHSS risk factors (5, 10-14).