PRTN3 and cancer: In gender-, ANCA-, and time period specificity-stratified analyses, SIR of cancer was not significantly increased for males of 1.27 (95% CI 0.88 to 1.83), in the C-ANCA/PR3-ANCA positive group of 1.17 (95% CI 0.78 to 1.74) and in the 1988–2002 time period of 1.14 (95% CI 0.78 to 1.68).