Similar to previously published results (9), B6.TNF−/− mice showed a significant increase of IFN-γ (Figure 3C) compared to that in B6.WT (day 28 after infection: mean ± SD, 269.45 ± 163.56 versus mean ± SD, 3.50 ± 1.49; day 35 after infection: mean ± SD, 668.39 ± 424.14 versus mean ± SD, 3.50 ± 2.46; day 42 after infection: mean ± SD, 766.03 ± 622.3 versus mean ± SD, 6.14 ± 4.11). The gene discussed is IFNG; the disease is infection.