No significant difference in the percentage of pDCs, CD103+ DCs, and CD11b+ cDCs was observed in the lungs of BALB/c and IL-1R−/− mice after C. neoformans 52D infection; however, at day 21 postinfection, there was a significantly higher percentage and number of AMs in BALB/c compared to IL-1R−/− mice (Figures 6A,B,D). The gene discussed is ITGAM; the disease is infection.