TNF and angina pectoris: Bao Xin decoction (another formula to treat PSCS with IHD) was effective in curing CAD with stable angina pectoris and acting by inhibiting serum interleukin 6 (IL-6), intercellular adhesion molecule 1 (ICAM-1) and tumor necrosis factor-α (TNF-α) levels and decreasing inflammatory reactions (Peng et al., 2011).