Importantly, two studies in China demonstrated that MMP9 levels in the blood decreased significantly after treatment with Shan Zha Xiao Zhi Decoction (Li, 2011; Wang et al., 2012b) or Danlou Tablet (Wang et al., 2012a) (another two formulas use to treat PSCS with IHD) compared with the levels prior to treatment (p < 0.01). The gene discussed is MMP9; the disease is myocardial ischemia.