Similarly, CoQ provision did not alter signalling responses or GLUT4 expression in any in vitro models of insulin resistance (Figure 5—figure supplement 1N–Q) despite improved insulin-stimulated HA-GLUT4 translocation, 2DOG uptake and suppression of lipolysis under these conditions (Figure 4B–C, Figure 4—figure supplement 1A). Here, SLC2A4 is linked to Insulin resistance.