INS and diabetes mellitus: Over the median follow-up of 67 months (IQR 30-110), crude revascularization rates (PCI or CABG) were 10% in Group A, 26% in Group B and 11.1% in Group C. A stepwise increase in the rates of revascularization over time, from no diabetes to non-insulin and insulin treated diabetes, was demonstrated in each of the 3 baseline cohorts (p < 0.001; Figs. 1a, b, 2a).