NFKB1 and ischemic stroke: In agreement with earlier experimental evidence arguing against the utility of OEA as neuroprotectant prior to ischemic stroke [72], it can be suggested that in our experimental setting the PPAR-alpha receptor is playing a dual role, both anti-inflammatory, likely via repression of NF-kB signalling [73], and anti-oxidative stress by enhancing lipoperoxide degradation [74].