In fact, in these studies, the C-T polymorphism of the BTN2A1 gene allele was significantly associated with the myocardial infarction [169,170], dislipidema [171,172,173], chronic kidney diseases (CKD) [172,174,175,176], hypertension [177,178,179], type 2 diabetes mellitus [81], and metabolic syndrome [180] in Japanese individuals and in East Asian populations. This evidence concerns the gene BTN2A1 and chronic kidney disease.