An upgraded version of e-ALMANACH, called the e-POCT [105] combines (i) key clinical elements (demographics, symptoms and signs); (ii) input from sensors connected directly to a tablet and detecting parameters of severe illness (e.g., hypoxemia, tachycardia, severe anemia, and hypoglycemia); (iii) clinical predictor factors (e.g., fast breathing); (iv) results from a series of POC tests for host biomarkers, in particular, C-reactive protein (CRP) and procalcitonin (PCT). The gene discussed is CRP; the disease is anemia.