ITGA6 and colorectal carcinoma: As expected from previous studies [22,32], MYC, ITGA6 and ITGA6A mRNAs were found to be significantly increased in CRC relative to their matched resection margins and a close correlation between both ITGA6 and MYC and ITGA6A and MYC expression was observed (Figure 1a,b), consistent with the gene expression profiling of ITGA6 in public data sets of gene expression of colorectal cancer (GSE35896) revealing a positive correlation between ITGA6 expression and MYC-induced genes (Figure 1c).