WAS and infection: It is also likely that mycolactone will not be presented during infection as a monomeric, water-soluble molecule; rather it will be bound to and carried by host molecules with hydrophobic domains (e.g., WASP, N-WASP) and/or lipid assemblies (e.g., bacterial vesicles, host cell membranes, and likely other assemblies such as high density lipoproteins).