Two members of the family, SLC26A3 (DRA; downregulated in adenoma) [25] and SLC26A6 (PAT1; putative anion transporter-1) [24, 46], were reported to be expressed in the luminal membrane of pancreatic ducts and function as Cl−–HCO3− exchangers [9, 19, 20]. The gene discussed is SLC26A6; the disease is adenoma.