Interestingly, some phenotypes of the MYO6 KO mouse, such as hypertrophic cardiomyopathy and gliosis in the brain (Mohiddin et al., 2004, Osterweil et al., 2005), are reminiscent of mitochondrial diseases (Chinnery, 2015) and neurodegenerative disorders, respectively. This evidence concerns the gene MYO6 and mitochondrial disease.