VCAM1 and neoplasm: A few published preclinical studies have reported on the role of VCAM-1 in cellular proliferation, but none specifically addressed the role of VCAM-1 in tumor proliferation.53, 54 Although we acknowledge the small number of patients included in this imaging substudy, it noteworthy that the direction of the correlation between VCAM-1 and 18FLT-PET was upheld for SUVmax as well as SUVmean.