However, caution is advised for the use or supplementation of MLT in some autoimmune conditions, such as rheumatoid arthritis, asthma or organ transplantation as MLT has been reported to stimulate the function of the immune system via the production of interleukins (IL-1, IL-2, IL-6 and IL-12), interferon γ (IFN-γ), Th cells, cytotoxic T cells, and B- and T-cell precursors [44]. The gene discussed is IL6; the disease is rheumatoid arthritis.