Similarly, GDF‐15 levels were also independently associated with all‐cause mortality, as was shown previously.14, 17 Uric acid was previously shown to be a powerful prognostic marker in patients with chronic heart failure, and uric acid levels were associated with GDF‐15.14, 49 In the present study, both GDF‐15 and sST2 were superior to uric acid for prediction of all‐cause mortality. The gene discussed is GDF15; the disease is congestive heart failure.