Growth differentiation factor (GDF)‐15 and soluble ST2 (sST2) are well‐established prognostic markers for mortality in acute and chronic heart failure12, 13, 14, 15, 16, 17 as well as in acute myocardial infarction.18 Inflammation and myocardial fibrosis, with subsequent ventricular remodelling and impairment of systolic function, are important pathophysiological mechanisms for VTs in patients with DCM.19, 20 Both GDF‐15 and sST2 show strong correlations with myocardial stress and fibrosis,21, 22, 23 and have been associated with sudden cardiac death in DCM.24, 25. The gene discussed is IL1RL1; the disease is familial dilated cardiomyopathy.