Indeed, the glycol epitopes on lubricin have the potential of strong interaction with selectin, galectins, and potentially other glycol‐binding proteins to facilitate inflammation (Ali et al., 2014; Jay, 1992; Jay, Harris, & Cha, 2001), however CACP patients do not present any signs of inflammation. Here, PRG4 is linked to camptodactyly-arthropathy-coxa vara-pericarditis syndrome.