SOD2 and hepatocellular carcinoma: Four relatively small studies (total 755 patients) investigated the association between HCC and MnSOD. 6, 7, 39, 40 All studies used an HCV‐infected comparison population, and three of the studies found a significant association.6, 39, 40 The remaining study did not, perhaps due to difference in ethnicities between this and the other studies (Caucasian rather than North African).