The Adolescent Type 1 Diabetes Cardio-Renal Intervention Trial (AdDIT; http://isrctn.com registration number 91419926) is the first interventional study in a group of normoalbuminuric adolescents with type 1 diabetes determined to be at high risk of developing kidney disease based on their urinary albumin creatinine ratio (ACR) [11]. Here, ALB is linked to type 1 diabetes mellitus.