Of note, Ad E1A was detected in the normoxic regions of d19-, a2bm-d19-, or Ha2bm-d19-treated tumors, whereas only Ha2bm-d19 was detected in abundance within the hypoxic tumor region (HIF-1α-positive) with no spots being observed for d19- or a2bm-d19-treated tumors (Fig. 5C). Here, DHTKD1 is linked to neoplasm.