Furthermore, ZAK mRNA upregulation was associated with significantly reduced survival in many TCGA solid cancer types, such as breast invasive carcinoma, brain lower grade glioma, cervical squamous cell carcinoma, lung adenocarcinoma, and renal papillary cell carcinoma (Figs. 4a, b and Supplementary Figure S6). The gene discussed is MAP3K20; the disease is lung adenocarcinoma.