Additional demographic information and clinical characteristics included Karnofsky performance status(KPS), alpha-fetoprotein(AFP), Child-Pugh classification, Barcelona Clinic Liver Cancer stage(BCLC stage), tumour size, intrahepatic tumour number, prior treatments, radiation technique, lymph node metastases(LN metastases), distant metastases, smoking status and drinking status (Table 1). This evidence concerns the gene AFP and liver cancer.