They also exhibited a lower production of ABCG2(Fig 7A, 7B, 7C, 7D, 7E and 7F) which is a ATP-binding cassette sub-family G member 2 (ABCG2) and human breast cancer resistance protein (BRCP) that expels chemotherapeutic drugs like mitoxantrone and topotecan out of the cells and imparts chemosensitivity[53].miR-15a therefore,augments the response of MDAMB-231 towards anti-cancer drugs. This evidence concerns the gene ABCG2 and cancer.