Theincidence for HF hospitalizations was 2.5 events per 100 person years of follow-up.Multivariable adjusted predictors for incident HF are presented in Table 2, and include BMI (HR1.40 [95%CI 1.17; 1.66], p = 0.0002), chronic kidney disease (2.27 [1.49; 3.45], p =0.0001), diabetes mellitus (2.13 [1.41; 3.24], p = 0.0004), QTc interval (1.25[1.04; 1.49], p = 0.018), BNP (2.19 [1.73; 2.77], p<0.0001), diastolic bloodpressure (0.79 [0.65; 0.96], p = 0.016), history of arrhythmia intervention (0.54[0.36; 0.80], p = 0.003) and serum chloride (0.82 [0.70; 0.96], p = 0.015). The gene discussed is NPPB; the disease is chronic kidney disease.