Moreover, down‐regulation of ARID1A decreased the levels of apoptosis in cancer cells and induced resistance to the killing effect of cisplatin.29 Our current data indicate that IC50 concentrations of paclitaxel are inversely correlated with ARID1A and VMP1/MIR21 mRNA levels (Figures 2 and S2). This evidence concerns the gene ARID1A and cancer.