And their transcription is mediated via RNA polymerase II.11, 12 Evidences have already indicated that lncRNAs can regulate gene expression at the epigenetic, transcriptional and post‐transcriptional levels.13 For example, lncRNA CCAT2, which is up‐regulated in colorectal cancer (CRC), can enhance tumour invasion and metastasis by regulating c‐Myc transcription and activate the Wnt signalling pathway.14 LncRNA CCAT1 can promote the progression of gastric carcinoma depending on the post‐transcriptional activity of c‐Myc.15 This evidence concerns the gene MYC and neoplasm.