Radionuclide 64Cu is a positron emitting copper isotope and 64CuCl2 was used as a radiotracer for noninvasive assessment of disturbance of cerebral copper fluxes in traumatic brain injury [28] and age-dependent changes of copper fluxes in Atp7b-/- knockout mouse model of Wilson’s disease [25]. Here, ATP7B is linked to Wilson disease.