CRP and diabetes mellitus: A growing body of evidence showed that systemic inflammation diminished the activity of antioxidant enzymes and total antioxidant capacity.11 High sensitive C-reactive protein (hs-CRP) and malondialdehyde (MDA) are markers of systemic inflammation and oxidative stress particularly in subjects with diabetes and CVD.12 Hs-CRP is a new biomarker for predicting the risk of cardiovascular events.