Out of 24 isolates from sheep suspected of enterotoxemia, 4 (16.66%) carried cpb2 while 2 (8.34%) were detected positive for cpe gene in toxinotype D. Among healthy sheep, 8 (9.30%) carried cpb2 while 1 (1.17%) isolate harbored cpe gene in toxinotype D out of 86 isolates (Table-4). The gene discussed is CPE; the disease is enterotoxemia.