Analysis of SMARCA2-silenced A549-wt cells pretreated with 1000 U/mL IFN-α 24 h prior to H7N7-RL infection revealed that in fact 8.6% of cells were positive for both MxA and viral nucleoprotein (NP), compared to 0.1% in the non-targeting (NT) control knockdown (Fig. 2b and Supplementary Figure S6b). Here, IFNA1 is linked to infection.