Therefore, to evaluate whether increased EPOR signaling in the hMtEPOR mice led to increased expression of inflammatory cytokines associated with AMD and known to drive LCNV development, we measured the mRNA expression at three and seven days post-laser treatment of several cytokines in RPE/choroids, particularly those cytokines produced by macrophages and previously reported in association with neovascular AMD10. This evidence concerns the gene EPOR and age-related macular degeneration.