The standard four-drug anti-TB treatment improved his TB clinical symptoms, including fever, chest pain, and left pleural effusion; however, abnormal liver function was noted (AST: 303 IU/L; ALT: 499 IU/L; and total bilirubin: 0.56 mg/dL) after 6 weeks of treatment, which resolved (ASL: 26 IU/L; ALT: 34 IU/L; total bilirubin: 0.1 mg/dL) after the interruption of anti-TB treatment. This evidence concerns the gene GPT and Pleural effusion.