The major therapeutic approach for the treatment ofbenign and metastasized cancer is chemotherapy; however, this treatment suffers fromseveral limitations including (1) most chemotherapeutic drugs lack selectivitytoward cancer cells and hence result in severe toxicity and side effects10,11 and (2)P-glycoproteins in the cancer cells activate and mediate multidrug resistance inmalignant cells.12,13 Heterogeneous cell populations in individual cancers ordifferent tumors also give rise to a variety of drug-resistant cancer stem cells14 that contribute to tumor relapse. Here, ABCB1 is linked to cancer.