Monocyte chemoattractant protein-1 (MCP-1) plays an important role in the development of allergic inflammatory reactions by recruiting various immune cells, which is associated with diverse autoimmune diseases.[4] In addition, Singh et al[5] found the level of urinary MCP-1 in LN patients was significantly higher than those without LN, and correlated to the severity of LN, which indicated MCP-1 might be a biological indicator of LN. The gene discussed is CCL2; the disease is autoimmune disease.