In addition, transcripts of components of the acute phase response and fibrinolysis important for the clearing of pathogens and healing of damaged tissue (e.g. matrix metalloproteinases and inhibitors: Mmp3, Mmp8, Mmp10, Timp1, Saa3, Clec4e, Clec4d, Chil1, F10, Plet1) [26, 27] reactive compound protection (cytochrome P450/Cyp1b1, Arg1) [28, 29], as well as metal ion scavenging proteins (e.g. haptoglobin, lipocalin, calprotectin S100A8/9) were strongly enriched during the infection with both Y. pseudotuberculosis strains. Here, S100A8 is linked to infection.