In line with these findings, genes involved in autophagy, such as BENC1 and LC3 are monoallelically deleted in 94% of HGSOCs; the deletion of BECN1 and LC3 in ovarian cancer cell lines not derived from HGS-OvCa induces a considerable sensitization to autophagy inhibitors [16]. Here, MAP1LC3A is linked to ovarian carcinoma.