In line with these findings miR-200a levels were found to be downregulated in CD133+ ovarian cancer cells compared to the levels observed in CD133− cells: overexpression of this miR in CD133+ cells inhibited cell migration and invasiveness through a mechanism at least in part mediated through E-Cadherin repressor ZEB2 targeting with consequent increase in E-Cadherin expression level [290]. Here, PROM1 is linked to ovarian cancer.