The miR-200 family plays a critical role in the suppression of epithelial-to-mesenchymal transition (EMT) and tumor cell migration, invasion, and metastasis by directly targeting ZEB1 and ZEB2 transcription factors and the level of miR-200s are important regulators of EMT in ovarian cancer cells [284,285,286]. The gene discussed is ZEB2; the disease is ovarian cancer.