CD44 and ovarian cancer: In fact, Meirelles and coworkers isolated from ovarian cancer cell lines a fraction of stem/progenitor cells (isolated according to CD44, CD24 and EpCAM positivity and E-cadherin negativity) and showed that, while unseparated original cell lines are inhibited by these drugs, these cells were stimulated by doxorubicin or cisplatin, [249].