Other than imprinted genes, disease-relevant gene sets identified for bimodal NORED-associated genes included nasopharyngeal carcinoma (22 genes, q=5.28×10−06), genes upregulated in mutated KRAS lung cancer model (10 genes, q=7.69×10−4), pancreatic cancer (6 genes, q=4.05×10−3), TP53 targets (11 genes, q=2.24×10−2), Alzheimer's disease upregulated genes (13 genes, q=3.07×10−2), female fertility (3 genes, q=9.22×10−3) and metabolic syndrome (11 genes, q=2.53×10−2; Supplementary Table S6). This evidence concerns the gene TP53 and early-onset autosomal dominant Alzheimer disease.