APOE and hyperlipidemia: In vivo studies revealed that miR-26a overexpression attenuated hyperlipidemia by reducing the concentrations of TC, TG, LDL-C, and HDL-C, inhibited atherosclerotic lesion and inflammatory response in HFD-fed apoE−/− mice, suggesting the anti-arteriosclerotic effects of miR-26a in vivo.