Furthermore, marked splenomegaly and high platelet counts in coexpressed p190/ p210 patients were reported by Arana-Trejo (15) although we did not find a significant difference for p190/p210 transcripts and platelet count (p=0.12) and also in the relationship between p190/p210 transcripts and splenomegaly (p=0.13). This evidence concerns the gene EVPL and Splenomegaly.