The obtained results significantly broaden the knowledge about the anticancer effects of coumarin compounds and their effect on the expression of MDR1, BCRP, LRP, and MRP multidrug induction genes of tumor cells derived from the human hematopoietic system: CEM/C1, CCRF/CEM, HL-60, HL-60/MX1, and HL-60/MX2. Here, ABCG2 is linked to neoplasm.