Last, but not least, anti-CD38 mAbs are attracting the interest in many other B-cell malignancies expressing surface CD38 including CLL, mantle cell lymphoma (MCL), diffuse large B-cell lymphoma (DLBCL), and transformed follicular lymphoma (FL) (NCT02413489) (44, 52, 61). This evidence concerns the gene CD38 and diffuse large B-cell lymphoma.