MDM2 and pancreatic neoplasm: The initiation, progression, and metastasis of human pancreatic cancer have been attributed to the mutation and deletion of multiple tumor suppressor genes (e.g., APC, TP53, etc.)(Duffy et al., 2014; Lesko et al., 2014) and the overexpression and aberrant activation of multiple oncogenes (e.g., CTNNB1, MDM2, etc.)(Qin et al., 2012; Thakur and Mishra, 2013; Voronkov and Krauss, 2013; Lemos et al., 2016).