Therefore, based on the higher secretion of IL-10 and the lower levels of IL-1β and iNOS mRNAs observed in EPS CG11/carrageenan treated rats in the peritonitis model, it could be assumed that the intraperitoneal injection of EPS CG11 probably influenced the peritoneal macrophages to acquire the immunosuppressive properties. This evidence concerns the gene IL10 and peritonitis.