Used as a Drp1-inhibitor, mdivi-1 attenuated neuronal apoptosis in animal models of brain ischemia (Zhang et al., 2013; Wang et al., 2014) and epilepsy (Qiu et al., 2013; Xie et al., 2016), both in vivo and in vitro, and reduced oxidative stress and synaptic depression in a model of Alzheimer’s disease (Baek et al., 2017). The gene discussed is DNM1L; the disease is brain ischemia.