As single-nucleotide polymorphisms (SNPs) in the 3′-untranslated region (3'UTR) of genes can affect gene expression and disease susceptibility [21], the rs3745368 SNP in the 3'UTR of the resistin gene might have an influence on resistin gene expression and thus influences the risk for the development of diabetes and hypertension [22]. The gene discussed is RETN; the disease is hypertensive disorder.